Prevalence, Complications, and Hospital Charges Associated with Use of Bone-Morphogenetic Proteins in Spinal Fusion Procedures.

Nov 16, 2011 by

Cahill KS, Chi JH, Day A, Claus EB.

JAMA.  2009; 302: 58-66.

PMID: 1956744

This study looked at the use of BMP and resulting complications and costs in an incredibly large database of over 300,000 fusion patients!  BMP substantially increased cervical complications costs when used cervically or lumbarly.  This paper raises important questions about BMP use for the current era of economic contraction.


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